2021 Mercedes-Benz E 350 E problems, complaints & recalls
Safety recalls (1)
Communication: Auto Crash Notification 2021-02-05 · campaign 21V058000 · 1,292,258 vehicles
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.
Risk: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.
Fix: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.
Service bulletins (108)
Technical service bulletins are repair instructions manufacturers send dealers for known issues. Unlike recalls, the fix is not automatically free — but naming the bulletin at the service desk can save diagnosis time and support goodwill repairs.
Service Brakes 2026-09-22 · LI42.10-P-078779 · Service Bulletin/Repair Instructions
complaint repeat workshop visit for vehicle vibration while braking from 60mph. note: although the symptom is similar to a tire or wheel vibration, it is usually readily noticeable that it is distinctly different if it happens at all times or only while braking. cause although the cause of the vibra
Structure:body 2026-09-14 · LI82.62-P-078631 · Service Bulletin/Repair Instructions
complaint clanking noise from the area of the speakers in the doors. cause under analysis. remedy to narrow down the cause, first of all remove the door trim. • if the noise continues to occur even with the door trim removed, then continue the diagnosis working towards the speaker and if necessary,
Structure:body 2026-08-06 · LI82.62-P-078631 · Service Bulletin/Repair Instructions
complaint clanking noise from the area of the speakers in the doors. cause under analysis. remedy to narrow down the cause, first of all remove the door trim. • if the noise continues to occur even with the door trim removed, then continue the diagnosis working towards the speaker and if necessary,
Electrical System 2026-07-27 · NCU - 2026010004 · Service Campaign
• always use the latest xentry diagnosis software release with all available add-ons. • make sure to follow the operation steps exactly as described in xentry diagnosis! • use a battery charger to ensure sufficient power supply of the vehicle on-board electrical system battery (greater than 12.5 v).
Power Train 2026-07-14 · LI35.30-P-058566 · Service Bulletin/Repair Instructions
single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). the noise is heard once in each instance when changing direction of travel. note: sound file in attachment cause if the complaint is eliminated by experimentally loosening the outboard collar n
Visibility/Wiper 2026-05-19 · LI82.30-P-059239 · Service Bulletin/Repair Instructions
complaint there are several types of complaint about noises or poor windshield wiper wiping performance: a: wiper blades squeaking, chattering, shuddering b: the windshield is not wiped completely (streaking) c: during the downward movement water is pulled back onto the windshield from the a-pillar
Showing the 6 most recent of 108 bulletins. Search all of them free at nhtsa.gov.
What owners report
No detailed complaint narratives on file.
Excerpts of consumer complaints filed with NHTSA, lightly truncated. They are owner statements, not verified findings.