2010 Mercedes-Benz E350 problems, complaints & recalls
Most-reported problem areas: Air Bags (65) · Fuel/Propulsion System (17) · Suspension (12)
🧭 Reliability snapshot
Compared against other Mercedes-Benz E350 model years — complaint volume vs the model's median year, recalls and severity. How we score →
🛣️ Complaints by mileage
76 NHTSA complaints that reported an odometer reading.
Safety recalls (4)
Engine And Engine Cooling:engine:engine Control Module (Ecu/Ecm):software 2022-03-18 · campaign 22V168000 · 22 vehicles
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2010 E350, 2014 G550, 2008-2009 C300, 2008 C350, 2009 CLK550, 2007 SL550, SLK280, and 2008 SLK350 vehicles. Various control units may have been updated with incorrect software configuration during a service repair. This can result in various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions, including stability and traction control.
Risk: Various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions including stability and traction control, can increase the risk of a crash.
Fix: Dealers will update the software configuration on the affected control units, free of charge. Owner notification letters were mailed May 3, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040003.
Air Bags:frontal:passenger Side:inflator Module 2018-01-10 · campaign 18V043000 · 132,167 vehicles
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2013 C250, C250 Coupe, C350 Coupe 4Matic, C300 4Matic, C350, C350 Coupe, C63 AMG, C63 Coupe, E350 Cabrio, E350 Coupe, E550 Cabrio, E350 Coupe 4Matic, E550 Coupe, GLK350 4Matic, GLK250 Bluetec 4Matic, GLK350, SLS Coupe, SLS AMG GT Coupe, and SLS Roadster vehicles sold, or ever registered, in the states of Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern
Risk: An inflator explosion may result in sharp metal fragments striking the driver or other occupants resulting in serious injury or death.
Fix: MBUSA will notify owners, and dealers will replace the passenger frontal air bag module, free of charge. Mercedes issued an interim notification to owners on February 23, 2018. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.
Air Bags:frontal:passenger Side:inflator Module 2016-05-26 · campaign 16V363000 · 258,163 vehicles
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2008-2011 C300 Sedan, C300 4matic Sedan, C350 Sedan, C63 AMG Sedan vehicles, 2010-2011 GLK350, GLK350 4-Matic and E350 Coupe vehicles, 2011 SLS AMG, E350 Convertible, E550 Coupe and E550 Convertible vehicles originally sold, or ever registered, in Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin I
Risk: An inflator rupture may result in metal fragments striking the vehicle occupants resulting in serious injury or death.
Fix: MBUSA will notify owners, and dealers will replace the passenger frontal air bag modules, free of charge. Owners were sent an interim notification October 2016. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.
Air Bags:frontal:driver Side:inflator Module 2016-02-11 · campaign 16V081000 · 711,159 vehicles
Defect: Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2009-2010 ML320 BlueTec 4Matic, GL320 BlueTec 4Matic and R320 CDI 4Matic, 2011 E350 Cabriolet and E550 Cabriolet, 2009-2011 ML350, ML350 4Matic, ML550 4Matic, ML63 AMG, and C63 AMG, 2010-2011 ML450 4Matic Hybrid, E350 Coupe, E350 4Matic, E550 Coupe, E550 4Matic, and E63 AMG, 2011-2012 GL350 BlueTec 4Matic and R350 BlueTec 4Matic, 2009-2012 GL450 4Matic, GL550 4Matic and R350 4Matic, 2007-2008 SLK280, SLK350, and SLK55 AMG, 2011-201
Risk: In the event of a crash necessitating deployment of the driver's frontal air bag, the inflator could rupture with metal fragments striking the driver or other occupants resulting in serious injury or death.
Fix: MBUSA will their notify owners, and Fiat Chrysler will notify the affected Chrysler owners. Dealers for the respective brands will replace the driver's frontal air bag module, free of charge. This recall began November 2016. Mercedes-Benz owners may contact MBUSA customer service at 1-800-367-6372 and Chrysler owners may contact Fiat Chrysler customer service at 1-800-853-1403.
Service bulletins (183)
Technical service bulletins are repair instructions manufacturers send dealers for known issues. Unlike recalls, the fix is not automatically free — but naming the bulletin at the service desk can save diagnosis time and support goodwill repairs.
Service Brakes 2026-09-22 · LI42.10-P-078779 · Service Bulletin/Repair Instructions
complaint repeat workshop visit for vehicle vibration while braking from 60mph. note: although the symptom is similar to a tire or wheel vibration, it is usually readily noticeable that it is distinctly different if it happens at all times or only while braking. cause although the cause of the vibra
Structure:body 2026-09-14 · LI82.62-P-078631 · Service Bulletin/Repair Instructions
complaint clanking noise from the area of the speakers in the doors. cause under analysis. remedy to narrow down the cause, first of all remove the door trim. • if the noise continues to occur even with the door trim removed, then continue the diagnosis working towards the speaker and if necessary,
Structure:body 2026-08-06 · LI82.62-P-078631 · Service Bulletin/Repair Instructions
complaint clanking noise from the area of the speakers in the doors. cause under analysis. remedy to narrow down the cause, first of all remove the door trim. • if the noise continues to occur even with the door trim removed, then continue the diagnosis working towards the speaker and if necessary,
Power Train 2026-07-14 · LI35.30-P-058566 · Service Bulletin/Repair Instructions
single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). the noise is heard once in each instance when changing direction of travel. note: sound file in attachment cause if the complaint is eliminated by experimentally loosening the outboard collar n
Structure:body 2026-06-02 · LI61.25-P-047933 · Service Bulletin/Repair Instructions
complaint the underfloor paneling is loose or sags (picture 1). cause mounting clips broken or not correctly engaged. remedy replace all mounting clips with collar nuts with shims (picture 2): adapter set (203 589 02 31 00) is required to perform the work. the underfloor paneling does not have to be
Electrical System 2026-05-26 · LI82.85-P-080507 · Service Bulletin/Repair Instructions
complaint after successful commissioning of the hermes control unit (n112/9) with xentry diagnosis dvd 03/2026, the message "sos - service not activated" appears on the instrument cluster. in addition, the following two conditions are also met: • hermes (n112/9) control unit: event code b15ce00 is a
Showing the 6 most recent of 183 bulletins. Search all of them free at nhtsa.gov.
What owners report
2026-09-30 · Steering“while i was driving the issues with the steering column module (scm) sudden loss of critical driver controls, erratic electrical behavior. it failed to communicate properly with the power steering system, alongside dashboard warnings for the electronic stability program (esp) and antilock braking system (abs) now my car is parked and i can’t drive …”
2026-04-10 · Service Brakes“i am writing to formally submit a complaint regarding my 2010 e350 (vin # [xxx] ). i have taken great pride in owning and maintaining this vehicle, and i want to share my concerns based on my recent experience. i have consistently kept this car well-maintained, following all recommended service schedules and ensuring that any necessary repairs wer…”
2026-02-17 · Lane Departure: Blind Spot Detection“all of sudden blind spot inoperable , turning signal to rt. , signal goes lt. or turning signal to lt. , signal goes to rt.…”
2026-01-19 · Structure:body“car was found to have the rear subframe corrosion for issue. but also the brake lines were corroded very badly. they should be covered under the rear subframe extended warranty replacement. the rear brake lines are an frequent issue and almost always shows up when the subframe begins to rot. also the pattern of the corrosion seems to be consiste…”
2025-11-24 · Service Brakes“it seems like brake lines corroded and need to be replaced. same issue in this car with subframe and that was taken care of by the extended warranty but brake lines were not part of extended warranty? that should be investigated further. rear subframe rust out and brake line corrosion are obviously related but mercedes is only addressing subframe. …”
2025-11-20 · Unknown Or Other“while driving once i start braking once the car is around 3mph it shifts from drive into park and abruptly comes to a stop. sometimes i am able to put it back into drive sometimes i have to turn the car off and reinsert the key just to get it back into drive. normally happens after an hour or so of driving the when i try to come to a complete stop …”
2025-09-24 · Service Brakes“my brakes failed, the rear brake lines had corroded. …”
2025-07-24 · Engine“fast acceleration then slow down goes into limp mode . happens when passing a car or taking off fast like entering into traffic . very dangerous. will be calling mercedes benz tomorrow. bought car used approximately 4 months ago. thanks…”
2025-07-18 · Service Brakes“my brakes went out while i was driving my family on a road trip. after getting towed i inspected the brake lines and they are absolutely destroyed. this is clearly a design flaw by mercedes. this needs to be recalled. you have to drop the rear subframe to repair this. absolutely ridiculous. …”
2025-04-14 · Fuel/Propulsion System“smell gasoline on driver side. can’t fill tank up or the smell is unbearable. gas consumption is high. engine light is on , suspension make a lot of noise, and ticking on driver side. …”
Excerpts of consumer complaints filed with NHTSA, lightly truncated. They are owner statements, not verified findings.