2022 Mercedes-Benz E 350 problems, complaints & recalls
Most-reported problem areas: Forward Collision Avoidance: Warnings (2) · Visibility/Wiper (1) · Vehicle Speed Control (1)
🧭 Reliability snapshot
Compared against other Mercedes-Benz E 350 model years — complaint volume vs the model's median year, recalls and severity. How we score →
Safety recalls (3)
Fuel System, Gasoline:delivery:fuel Pump 2023-12-21 · campaign 23V880000 · 79,676 vehicles
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Risk: A loss of drive power can increase the risk of a crash.
Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of NHTSA recall number 23V-445.
Fuel System, Gasoline:delivery:fuel Pump 2023-06-26 · campaign 23V445000 · 143,551 vehicles
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Risk: A loss of drive power can increase the risk of a crash.
Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Steering: Steering Wheel/Handle Bar 2022-03-25 · campaign 22V189000 · 8,396 vehicles
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
Risk: Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.
Fix: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.
Service bulletins (152)
Technical service bulletins are repair instructions manufacturers send dealers for known issues. Unlike recalls, the fix is not automatically free — but naming the bulletin at the service desk can save diagnosis time and support goodwill repairs.
Steering 2026-09-26 · LI46.10-P-080896 · Service Bulletin/Repair Instructions
complaint slight creaking noises when steering. cause noises may come from one or more sleeves of the horn contact plate. remedy remove the horn contact plate and check the sleeves for noise; see attached video. if necessary, apply lubricant to the sleeves.
Power Train 2026-09-26 · LI27.00-P-073124 · Service Bulletin/Repair Instructions
complaint customer complaints relating to automatic transmission 725.0 (nag3 classic /9g‑tronic automatic transmission) and 725.1 (nag3 facelift/9g‑tronic automatic transmission facelift) for faster, more effective and more targeted diagnosis, intelligent predictive repair (ipr) has been developed a
Service Brakes 2026-09-22 · LI42.10-P-078779 · Service Bulletin/Repair Instructions
complaint repeat workshop visit for vehicle vibration while braking from 60mph. note: although the symptom is similar to a tire or wheel vibration, it is usually readily noticeable that it is distinctly different if it happens at all times or only while braking. cause although the cause of the vibra
Engine 2026-09-17 · LI20.10-P-075374 · Service Bulletin/Repair Instructions
complaint red coolant warning in instrument cluster. fault codes u019f00 or u019f87 current/stored in mrg1 control unit. cause various causes remedy perform guided test for fault code u019f with xentry diagnosis. verify the following connections are clean and tight. correct any problems and retest p
Structure:body 2026-09-14 · LI82.62-P-078631 · Service Bulletin/Repair Instructions
complaint clanking noise from the area of the speakers in the doors. cause under analysis. remedy to narrow down the cause, first of all remove the door trim. • if the noise continues to occur even with the door trim removed, then continue the diagnosis working towards the speaker and if necessary,
Power Train 2026-09-14 · LI27.10-P-075869 · Service Bulletin/Repair Instructions
complaint only vehicles with a variable transfer case are affected. this can be identified through control unit n45 or n15/7 in the quick test. when accelerating with light load, vibrations or jolting sensation may come from the drivetrain. it may be mistaken for a harsh shift. cause modified oil qu
Showing the 6 most recent of 152 bulletins. Search all of them free at nhtsa.gov.
What owners report
2026-10-10 · Forward Collision Avoidance: Warnings“2022 mercedes-benz e350 with driver assistance package. two incidents of uncommanded automatic braking with no vehicle ahead and no debris on the road: (1) october 7, 2026, 4:30 am — active brake assist braked automatically on a clear road in dark conditions; (2) second incident of the same kind, date unknown. no collision resulted, but sudden unco…”
2026-07-22 · Visibility/Wiper“i own a 2022 mercedes-benz e350. the front glass roof panel located directly above the windshield developed a large crack while the vehicle was parked. the crack extends nearly the full length of the panel and includes areas where the glass has separated along the fracture. i am not aware of any collision, road debris, or object striking the vehicl…”
2026-01-07 · Vehicle Speed Control“ this vehicle on an ongoing basis is reporting false speed limits. it consistently abruptly drops the indicated speed limit from 70mph on [xxx] northbound in salt lake city. the vehicle slows itself abruptly in traffic that is sometimes dense and traveling 70 to 80. an eventual rear end collision seems likely which could involve multiple vehi…”
2025-10-23 · Power Train“major issue found with engine cylinder head in various models with 2.0 liter turbo charged engines (engine code m260 or m264). cylinder heads have premature wear at valve seats, causing engine misfires and unsafe driving conditions. (sudden loss of power, even on freeways.) mercedes-benz had improved cylinder head design to mitigate this issue, t…”
2024-06-18 · Unknown Or Other“on june 16, 2024, while driving my 2022 mercedes e 350 with my two young children in the car, my sunroof suddenly and literally exploded. fortunately, the sunroof screen was closed, which prevented us from sustaining any direct injuries. however, the entire sunroof shattered and is now gone. the explosion sounded like a gunshot, causing immediate …”
2024-01-29 · Forward Collision Avoidance: Warnings“auto break suddenly activated during traffic with no obstruction ahead. also automatic headlamp mode inoperative comes on and off…”
2023-12-20 · Unknown Or Other“my vehicle suddenly stopped in the middle of road. it showed gas tank empty though tank had half tank gas. i would have been hit by a vehicle behind me. fortunately, there were no vehicles behind me. i filled the remaining half tank , then car started again. i believe that gas sensor was not working. i dropped the vehicle for service to the merce…”
2023-09-19 · Unknown Or Other“the panoramic sunroof exploded while inside the car without warning. contacted the dealership/service center on friday 9/15/2023, was told they have not received a memo regarding the panoramic sunroofs in the 2022 e350, however; this is a know problem. i was told that this is not covered of my warranty because they assume something had to hit the g…”
2023-08-23 · Fuel System, Gasoline · 14,403 mi“the contact owns a 2022 mercedes-benz e350. the contact stated that on several occasions while driving at various speeds, the vehicle decelerated while the accelerator pedal was depressed. the contact was able to turn off and restart the vehicle. an unknown warning light was illuminated. the vehicle was taken to the dealer where it was diagnosed a …”
Excerpts of consumer complaints filed with NHTSA, lightly truncated. They are owner statements, not verified findings.